主要从事“基于三键聚合构筑新型多功能高分子材料”、“新型AIE有机高分子功能材料的开发及构-效关系探究”以及“聚集诱导发光探针在高分子材料中的应用”等相关领域的研究。

科研论文：

一作或共一论文：

[1] T. Han, Z. S. Yao, Z. J Qiu, Z. Zhao, K. Y. Wu, J. G. Wang, Andrew W. Poon, Jacky W. Y. Lam*, and B. Z. Tang*, Photoresponsive spiro-polymers generated in situ by C–H-activated polyspiroannulation, Nat. Commun., 2019, 10, 5483.

[2]T. Han#, H. Q. Deng#, Z. J. Qiu, Z.Zhao, H. K. Zhang, H. Zou, Nelson L. C. Leung, G. G. Shan, Mark R. J. Elsegood, Jacky W. Y. Lam*, and B. Z. Tang*, Facile multicomponent polymerizations toward unconventional luminescent polymers with readily openable small heterocycles,J. Am. Chem. Soc., 2018, 140, 5588–5598.

[3]T. Han, Z.Zhao, Jacky W. Y. Lam* and B. Z. Tang*, Monomer stoichiometry imbalance-promoted formation of multisubstituted polynaphthalenes by palladium-catalyzed polycouplings of aryl iodides and internal diynes,Polym.Chem., 2018, 9, 885−893.

[4]T. Han, C.Gui, Jacky W. Y. Lam, M. J. Jiang, N. Xie, Ryan T. K. Kwok, and B. Z. Tang*,High-contrast visualization and differentiation of microphase separation in polymer blends by fluorescent AIE probes,Macromolecules, 2017,50, 5807−5815.

[5]T. Han, Z.Zhao, H. Q. Deng, Ryan T. K. Kwok, Jacky W. Y. Lam* and B. Z. Tang*,Iridium-catalyzed polymerization of benzoic acids and internal diynes: a newroute for constructing high molecular weight polynaphthalenes without the constraint of monomer stoichiometry,Polym. Chem.,2017,8,1393–1403.

[6]T. Han#, X.G. Gu#, Jacky W. Y. Lam, Anakin C. S. Leung, Ryan T. K. Kwok, T. Y. Han, B.Tong, J. B. Shi, Y. P. Dong* and B. Z. Tang*, Diaminomaleonitrile-based Schiff bases: aggregation-enhanced emission, red fluorescence, mechanochromism and bioimaging application,J. Mater. Chem. C,2016, 4,10430-10434.

[7]T. Han, H.Q. Deng, Chris Y. Y. Yu, C. Gui, Z. G. Song, Ryan T. K. Kwok, Jacky. W. Y. Lam*and B. Z. Tang*, Functional isocoumarin-containing polymers synthesized by rhodium-catalyzed oxidative polycoupling of aryl diacid and internal diyne,Polym.Chem., 2016, 7, 2501–2510.

[8]T. Han#, Y.J. Zhang#, X. Feng,* Z. G. Lin, B. Tong, J. B. Shi, J. G. Zhi and Y. P. Dong*,Reversible and hydrogen bonding-assisted piezochromic luminescence for solid-state tetraaryl-buta-1,3-diene,Chem. Commun., 2013, 49, 7049-7051.

[9] T. Han, L. J. Liu, D. Wang, J. L. Yang*, and B. Z. Tang*, Mechanochromic fluorescent polymers enabled by AIE processes,Macromol. Rapid Commun., 2020, 2000311.

[10] T. Han, X. N. Wang, D. Wang*, and B. Z. Tang*, Functional polymer systems with aggregation-induced emission and stimuli responses, Top. Curr. Chem., 2021, 379, 7.

[11] T. Han, D. Y. Yan, Q. Wu, N. Song, H. K. Zhang, and D. Wang*, Aggregation-induced emission: a rising star in chemistry and materials science, Chinese J. Chem., 2020, 39, 677-689.

[12] J. C. Zhu(#),T. Han(#), Y. Guo,P. Wang, H. L. Xie,* Z. G. Meng, Z. Q. Yu,* and B. Z. Tang*,Design and synthesis of luminescent liquid crystalline polymers with “jacketing” effect and luminescentpatterning applications,Macromolecules,2019, 52, 3668-3679. (#Co-first author).

[13] H. Q. Deng(#),T. Han(#), E. G. Zhao, RyanT. K. Kowk, Jacky W. Y. Lam* and B. Z. Tang*, Multicomponent click polymerization: a facile strategy toward fused heterocyclic polymers,Macromolecules,2016, 49, 5475−5483.(#Co-first author).

[14] Q. Q. Gao, T. Han, X. L. Liu, Z. J. Qiu, S. J. Liu, P. F. Wei, X. N. Wang, Jacky W. Y Lam*, and B. Z. Tang*, Facile synthesis of functional processable fluoropolydienes by alkyne-based multicomponent polycouplings, Macromolecules, 2020, 53, 9859–9868. (#Co-first author).

[15] T. Han*, S. S. Chen, X. N. Wang, X. Y. Fu, H. F. Wen, Z. Y. Wang, D. Wang, A. J. Qin*, J. L. Yang*, and B. Z. Tang*, Autonomous visualization of damage in polymers by metal-free polymerizations of microencapsulated activated alkynes, Adv. Sci., 2022, 9, 2105395.

通讯作者论文：

[1] K. Wang, J. K. Liu, P. Y. Liu, D. Wang, T. Han*, and B. Z. Tang*, Multifunctional fluorescent main-chain charged polyelectrolytes synthesized by cascade C‒H activation/annulation polymerizations, J. Am. Chem. Soc., 2023, 145(7), 4208-4220

[2] K. Wang#, S. S. Yan#, T. Han*, Q. Wu, N. Yan, M. M. Kang, J. Y. Ge, D. Wang*, B. Z. Tang*, Cascade C‒H-activated polyannulations toward ring-fused heteroaromatic polymers for intracellular pH mapping and cancer cell killing, J. Am. Chem. Soc., 2022, 144(26), 11788-11801.

[3] J. Li, J. X. Wang, J. Y. Zhang, T. Han*, X. Y. Hu, Michelle M. S. Lee, D. Wang*, and B. Z. Tang*, A facile strategy of boosting photothermal conversion efficiency through state transformation for cancer therapy, Adv. Mater., 2021, 33, 2105999.

[4] S. S. Chen, T. Han*, J. K. Liu, X. T. Liang, J. L. Yang*, and B. Z. Tang*, Visualization and monitoring of dynamic damaging-healing processes of polymers by AIEgen-loaded multifunctional microcapsules, J. Mater. Chem. A, 2022, 10(29), 15438-15448.

[5] X. Su, T. Han*, N. Niu, H. X. Li, D. Wang*, and B. Z. Tang*, Facile multicomponent polymerizations toward multifunctional heterochain polymers with α,β-unsaturated amidines, Macromolecules, 2021, 54, 9906-9918.

[6] X. N. Wang, T. Han*, J. Y. Gong, P. Alam, H. K. Zhang, Jacky W. Y. Lam*, B. Z. Tang*, Diversity-oriented synthesis of functional polymers with multisubstituted small heterocycles by facile stereoselective multicomponent polymerizations, Macromolecules, 2022, 55 (11), 4389-4401.

[7] X. Su^#, R. H. Liu^#, Y. Li, T. Han*, Z. J. Zhang, N. Niu, M. M. Kang, S. Fu, D. L. Wang, D. Wang*, and B. Z. Tang*, AIE-active poly(phenyleneethynylene)s for fluorescence and Raman dual-modal imaging and drug-resistant bacteria killing, Adv. Healthcare Mater., 2021, 2101167.

[8] X. Su#, Q. Q. Gao#, D. Wang, T. Han*, and B. Z. Tang*, One-step multicomponent polymerizations for the synthesis of multifunctional AIE polymers, Macromol. Rapid Commun., 2021, 42(6), 2000471. 

[9] X. N. Wang, T. Han*, Jacky W. Y. Lam*, and B. Z. Tang*, In situ generation of heterocyclic polymers by triple-bond based polymerizations, Macromol. Rapid Commun., 2021, 42(24), 2100524.

[10] J. X. Wang, J. Li, L. Wang, T. Han*, D. Wang*, and B. Z. Tang*, AIEgen-based polymer nanocomposites for imaging-guided photothermal therapy, ACS Appl. Polym. Mater., 2020, 2 (10), 4306-4318.

[11] X. L. Liu, T. Han*, Jacky W. Y. Lam*, and B. Z. Tang*, Functional heterochain polymers constructed by alkyne multicomponent polymerizations, Macromol. Rapid Commun., 2021, 42(6), 2000386.

[12] D. Y. Fan, D. Wang, T. Han*, and B. Z. Tang*, Fused heterocyclic polymers with aggregation-induced emission: synthesis and applications, ACS Appl. Polym. Mater., 2022, 4(5) , 3120–3130.

[13] J. Y. Xie, N. Niu, X. Y. Fu, X. Su, D. Wang, A. J. Qin, T. Han*, and B. Z. Tang*, Catalyst-free synthesis of diverse fluorescent polyoxadiazoles for the facile formation and morphology visualization of microporous films and cell imaging, Chem. Sci., 2023, 14(4), 903-915.

[14] D. Y. Fan, F. Zhang, J. Cui, D. Wang, T. Han*, and B. Z. Tang*, Synthesis of fluorescent multisubstituted polyquinolines by cascade C−H activation-based polyannulations of isonicotinamides and diynes, Sci. China Chem., 2023, 66(4). 1139-1149.

[15] H. W. Yan#, Y. L. He#, D. Wang, T. Han*, and B. Z. Tang*, Aggregation-induced emission polymer systems with circularly polarized luminescence, Aggregate, 2023, early view, e331.

[16] X. Su^#, Z. R. Bao^#, W. Xie, D. L. Wang, T. Han*, D. Wang*, and B. Z. Tang*, Precise planar-twisted molecular engineering to construct semiconducting polymers with balanced absorption and quantum yield for efficient phototheranostics, Research, 2023, 6, article ID: 0194.

共同作者论文：

[1] H. Q. Deng, T. Han, E. G. Zhao, Ryan T. K. Kwok, Jacky W. Y. Lam* and B. Z. Tang*, Multicomponent polymerization: development of one-pot synthetic route to functional polymers using diyne, N-sulfonyl azide and water/ethanol as reactants, Polym. Chem., 2016, 7, 5646–5654.

[2] Z. J. Qiu, T. Han, Ryan T. K. Kwok, Jacky W. Y. Lam* and B. Z. Tang*, Polyarylcyanation of diyne: a one-pot three-component convenient route for in-situ generation of polymers with AIE characteristics, Macromolecules, 2016, 49, 8888−8898.  

[3] Y. B. Hu, T. Han, N. Yan, J. K. Liu, X. L. Liu, W. X. Wang, Jacky W. Y. Lam*, and B. Z. Tang*, Visualization of biogenic amines and in vivo ratiometric mapping of intestinal pH by AIE-active polyheterocycles synthesized by metal-free multicomponent polymerizations, Adv. Funct. Mater., 2019, 29, 1902240.  

[4] H. C. Huang#, Z. J. Qiu#, T. Han, Ryan T. K. Kwok, Jacky W. Y. Lam*, and B. Z. Tang*, Synthesis of functional poly(propargyl imine)s by multicomponent polymerizations of bromoarenes, isonitriles, and alkynes, ACS Macro Lett., 2017, 6, 1352-1356.  

[5] H. Q. Peng, X. Y. Zheng, T. Han, Ryan T. K. Kwok, Jacky W. Y. Lam, X. H. Huang and B. Z. Tang*, Dramatic differences in aggregation-induced emission and supramolecular polymerizability of tetraphenylethene-based stereoisomers, J. Am. Chem. Soc., 2017, 139, 10150–10156.  

[6] D. F. Dang, Z. J. Qiu, T. Han, Y. Liu, M. Chen, Ryan T. K. Kwok, Jacky. W. Y. Lam and B. Z. Tang*, 1+1>>2: Dramatically enhancing the emission efficiency of TPE-based AIEgens but keeping their emission color through tailored alkyl linkages, Adv. Funct. Mater., 2018, 28, 1707210.  

[7] Y. L. Zhang#, M. J. Jiang#, T. Han, X. T. Xiao, W. L. Chen, L. Wang, K. S. Wong*, R. Wang*, K. Wang*, B. Z. Tang*, K. S. Wu*, Aggregation-induced emission luminogens as color converters for visible-light communication, ACS Appl. Mater. Interfaces, 2018, 10, 34418–34426.  

[8] W. Yuan, W. W. Chi, T. Han, J. Du, H. K. Li,* Y. F. Li and B. Z. Tang*, Metal-free phenylpropiolate-azide polycycloaddition: efficient synthesis of functional poly(phenyltriazolylcarboxylate)s, Polym. Chem., 2018, 9, 5215–5223.  

[9] W. W. Chi, W. Yuan, J. Du, T. Han, H. K. Li,* Y. F. Li, and B. Z. Tang*, Construction of functional hyperbranched poly(phenyltriazolylcarboxylate)s by metal-free phenylpropiolate-azide polycycloaddition, Macromol. Rapid Commun., 2018, 39, 1800604.  

[10] X. L. Liu#, M. G. Li#, T. Han, B. Cao, Z. J. Qiu, Y. Y. Li, Q. Y. Li, Y. B. Hu, Z. Y. Liu, Z. Zheng, Jacky W. Y. Lam*, X. L. Hu*, and B. Z. Tang*, In Situ generation of azonia-containing polyelectrolytes for luminescent photopatterning and superbug killing, J. Am. Chem. Soc., 2019, 141, 11259-11268.  

[11] J. Wang, T. W. Bai, Y. Chen, C. B. Ye, T. Han, A. J. Qin*, J. Ling*, and B. Z. Tang*, Palladium/Benzoic acid-catalyzed regio- and stereoselective polymerization of internal diynes and diols through C(sp³)–H activation, ACS Macro Lett., 2019, 8, 1068-1074.  

[12] Q. Q. Gao, L. H. Xiong, T. Han, Z. J. Qiu, X. W. He, Herman H. Y. Sung, Ryan T. K. Kwok, Ian D. Williams, Jacky W. Y. Lam*, and B. Z. Tang*, Three-component regio- and stereoselective polymerizations towards functional chalcogen-rich polymers with AIE-activities, J. Am. Chem. Soc.,2019, 141, 14712-14719.  

[13] W. W. Chi, R. Y. Zhang, T. Han, J. Du, H. K. Li,* W. J. Zhang,* Y. F. Li, and B. Z. Tang*, Facile synthesis of functional poly(methyltriazolylcarboxylate)s by solvent- and catalyst-free butynoate–azide polycycloaddition, Chinese J. Polym. Sci., 2019, https://doi.org/10.1007/s10118-019-2316-y.  

[14] H. Q. Peng#, B. Liu#, J. K. Liu, P. F. Wei, H. K. Zhang, T. Han, J. Qi, Jacky W. Y. Lam, W. J. Zhang, and B. Z. Tang*, “Seeing” and controlling photoisomerization by (Z)‑/(E)‑isomers with aggregation-induced emission characteristics, ACS Nano, 2019,13, 12120-12126.

[15] Y. Y. Li#, S. J. Liu#, T. Han, H. K. Zhang, C. Chuah, Ryan T. K. Kwok, Jacky W. Y. Lam* and B. Z. Tang*, Sparks fly when AIE meets with polymers, Mater. Chem. Front., 2019, 3, 2207-2220.

[16] S. S. Chen, T. Han, Y. Zhao, W. J. Luo, Z. Zhang, H. B. Su, B. Z. Tang*, and J. L. Yang*, A facile strategy to prepare smart coatings with autonomous self-healing and self-reporting functions, ACS Appl. Mater. Interfaces, 2020, 12, 4870-4877.

[17] C. K. Ma, T. Han, M. M. Kang, E. Liarou, A. M. Wemyss, S. Efstathiou, B. Z. Tang, and D. Haddleton*, ACS Macro Lett., 2020, 9, 769−775.

[18] M. N. Lang, W. W. Chi, T. Han, Q. Z. Zhao, H. K. Li*, B. Z. Tang, and Y. F. Li, Synthesis of functional hyperbranched poly(methyltriazolyl-carboxylate)s by catalyst-free click polymerization of butynoates and azides, Chinese J. Polym. Sci., 2020, 38(11), 1171–1177.

[19] Z. J. Qiu#, Q. Q. Gao#, T. Han, X. L. Liu, Jacky W. Y Lam*, and B. Z. Tang*, One-pot three-component polymerization for in-situ generation of AIE-active poly(tetraarylethene)s using grignard reagents as building block, Polym. Chem., 2020, 11, 5601-5609.

[20] M. P. Fernández-Liencres, M. Moral, Y. L. Zhang, T. Han, M. J. Jiang, A. Garzón-Ruiz*, A. Navarro*, K. S. Wong, and B. Z. Tang*, Unraveling the photophysical and semiconducting properties of color converter luminogens with aggregation induced emission characteristics, J. Mater. Chem. C, 2020, 8, 16757-16768.

[21] N. Song#, Z. J. Zhang#, P. Y. Liu, D. H. Dai, C. Chen, Y. M. Li, L. Wang, T. Han, Y. W. Yang*, D. Wang*, B. Z. Tang*, Pillar[5]arene-modified gold nanorods as nanocarriers for multi-modal imaging-guided synergistic photodynamic-photothermal therapy, Adv. Funct. Mater., 2021, 31(21), 2009924.

[22] C. K. Ma, T. Han, N. Niu, L. Al-Shok, S. Efstathiou, D. Lester, S. Huband, and D. M. Haddleton*, Well-defined polyacrylamides with AIE properties via rapid Cu-mediated living radical polymerization in aqueous solution: thermoresponsive nanoparticles for bioimaging, Polym. Chem., 2022, 13(1), 58-68.

[23] C. K. Ma, T. Han, S. Efstathiou, A. Marathianos, H. A. Houck, and D. M. Haddleton*, Aggregation-induced emission poly(meth)acrylates for photopatterning via wavelength-dependent visible-light-regulated controlled radical polymerization in batch and flow conditions, Macromolecules, 2022, 55(22), 9908−9917.

[24] H. W. Yan, J. X. Quan, H. N. Qu, F. Zhu, Y. Q. Wang, M. K. Dhinakaran, T. Han, and H. B. Li*, Membranes with nanochannels based on pillar[6]arenes to separate xylenes, ACS Appl. Nano Mater., 2022, 5, 12, 18637-18644.

书籍专著：

T. Han, Jacky W. Y. Lam*, B. Z. Tang*. Fused(Hetero)Cyclic Polymers Synthesized by Alkyne-Based Polymerizations. In Synthetic Polymer Chemistry: Innovations and Outlook; RSC Polymer Chemistry Series; Z. Zhao, R. Hu, A. J. Qin, B. Z. Tang, Eds.; Royal Society of Chemistry.

专利信息：

[1] B. Z. Tang, T. Han, Z. J. Qiu. Functional spirocyclic polymers and methods of preparation thereof [P], US 10844163 B2, 24 November 2020.

[2] 唐本忠，丘子杰，朱景基，谢你，韩婷，椰西罗士，归晨，聚集诱导发光应用于掺杂型聚合物：玻璃化转变温度的检测和相分离形貌可视化，ZL201680065650.1, 2021. 07. 27.

[3]  唐本忠，韩婷，邓海琴，含有杂环的聚合物、其制备方法及其应用，ZL201910129837.9, 2022. 04. 26.

2022年度深圳市自然科学奖二等奖(2/5)